Articles on: maldi tof


The large-scale studies of structure and function of proteins (proteomics) are performed using a variety of analytical techniques from two-dimensional gel electrophoresis, immunoaffinity chromatography to tandem and MALDI-TOF mass spectrometry. The words “large-scale” in proteomics definition refers to the fact that the number of proteins that need to be evaluated is enormous. For example, the […]


John J. Kasianowicz from NIST and his colleagues created a 2D method for mass spectrometry capable of a single-molecule analysis based on the interaction between a nanometer-scale pore and analytes. The method is a “nano” version of Wallace Coulter patented technique that detects particles suspended in solution by driving them through a capillary which is […]


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